![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI) Isithombe Esifakiwe](https://cdn.globalso.com/nvchem/118-Re36H44N2O8Si-Uridine.jpg)
118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI)
| Izici Zomzimba Eziyinhloko | Inani | Isimo |
| Isisindo samangqamuzana | 660.83 | - |
| Ukuminyana (Kubikezelwe) | 1.24±0.1 g/cm3 | Izinga lokushisa: 20 °C; Cindezela: 760 Torr |
| pKa (Kubikezelwe) | 9.39±0.10 | Izinga Le-Acidic Elikhulu: 25 °C |
I-Canonical AMAMOTHEKA O=C1C=CN(C(=O)N1)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C= C5)C(O)C2O[Si](C)(C)C(C)(C)C
I-Isomeric SMILES
C(OC[C@H]1O[C@H]([C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O)N2C( =O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC= C5
I-InChI
I-InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-31(40)29(45-33(32)38-22-21-30(39)37-34( 38)41)23-44-36(24-11-9-8-10-12-24,25-13- 17-27(42-4)18-14-25)26-15-19-28( 43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/ m1/s1
Ukhiye we-InchI
KVHQIELPHWJPSY-WXQJYUTRSA-N
2 Amanye Amagama Alesi Sitho
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]uridine (ACI); 2′-O-tert-Butyldimethylsilyl-5′-O-(4,4′- dimethoxytrityl)uridine
I-Spectra iyatholakala
1H NMR
13C NMR
I-Hetero NMR
IMisa
| Izakhiwo ezitholakalayo |
| I-Biological |
| Amakhemikhali |
| Ukuminyana |
| I-Lipinski |
| Okuhlobene Nesakhiwo |
I-Biological
| Impahla | Inani | Isimo | Umthombo |
| I-Bioconcentration Factor | 2.21 x 105 | pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.21 x 105 | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.21 x 105 | i-pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.21 x 105 | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.21 x 105 | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.21 x 105 | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.20 x 105 | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 2.12 x 105 | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.54 x 105 | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 42500 | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Amakhemikhali
| Impahla | Inani | Isimo | Umthombo |
| Koc | 2.33 x 105 | pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | i-pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| Impahla | Inani | Isimo | Umthombo |
| Koc | 2.32 x 105 | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 2.23 x 105 | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 1.62 x 105 | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 44800 | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | i-pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.33 | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.32 | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 7.18 | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| logD | 6.62 | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| logP | 7.334±0.643 | Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Intrinsic Solubility | 3.5 x 10-5 g/L | Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | i-pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.6 x 10-5 g/L | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 5.0 x 10-5 g/L | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 1.9 x 10-4 g/L | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 3.5 x 10-5 g/L | Amanzi Angenabuffered pH 7.00; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Intrinsic Solubility | 5.3 x 10-8 mol/L | Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | i-pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| Impahla | Inani | Isimo | Umthombo |
| I-Molar Solubility | 5.3 x 10-8 mol/L | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.5 x 10-8 mol/L | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 7.6 x 10-8 mol/L | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 2.8 x 10-7 mol/L | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 5.3 x 10-8 mol/L | Amanzi Angenabuffered pH 7.00; Izinga lokushisa: 25 °C | (1) ACD |
| Isisindo samangqamuzana | 660.83 | ||
| pKa | 9.39±0.10 | Izinga Le-Acidic Elikhulu: 25 °C | (1) ACD |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Ukuminyana
| Impahla | Inani | Isimo | Umthombo |
| Ukuminyana | 1.24±0.1 g/cm3 | Izinga lokushisa: 20 °C; Cindezela: 760 Torr | (1) ACD |
| Ivolumu ye-Molar | 528.8±5.0 cm3/mol | Izinga lokushisa: 20 °C; Cindezela: 760 Torr | (1) ACD |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
I-Lipinski
| Impahla | Inani | Isimo | Umthombo |
| Amabhondi Ashintshashintshayo Ngokukhululekile | 13 | (1) ACD | |
| H Abamukelayo | 10 | (1) ACD | |
| H Abanikeli | 2 | (1) ACD | |
| H Isamba Somnikeli/Umamukeli | 12 | (1) ACD | |
| logP | 7.334±0.643 | Izinga lokushisa: 25 °C | (1) ACD |
| Isisindo samangqamuzana | 660.83 |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Okuhlobene Nesakhiwo
| Impahla | Inani | Isimo | Umthombo |
| Indawo ye-Polar Surface | 116 A2 | (1) ACD | |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
I-Spectra iyatholakala
1H NMR
13C NMR
![C30H29FN2O7 Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′- fluoro- (9CI, ACI)](https://cdn.globalso.com/nvchem/C30H29FN2O7-Uridine-300x300.jpg)
![C31H32N2O8 Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl- (9C I, ACI)](https://cdn.globalso.com/nvchem/C31H32N2O8-Uridine-300x300.jpg)
![C40H49N4O9P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] (ACI)](https://cdn.globalso.com/nvchem/C40H49N4O9P-Uridine-300x300.png)
