I-2-methyl-5-nitroimidazole
Imininingwane eyisisekelo:
Igama lamakhemikhali: 2-methyl-5-nitroimidazole;
Igama lesiNgisi: 2-methyl-5-nitroimidazole;
Inombolo ye-CAS: 88054-22
Ifomula yamangqamuzana: c4h5n3o2
Isisindo Molecular: 127.1
Inombolo ye-EINECS: 618-108-7
Ifomula yesakhiwo:
Izigaba ezihlobene: Izinto zokusetshenziswa; I-Pharmaceutical Intermediates; Izinto zokwakha amakhemikhali.
Ubuningi: 1.4 ± 0.1G / CM3
Iphuzu elibilayo: 399.5 ± 15.0 ° C ku-760 mmhg
Iphuzu elincibilikayo: 252-254ºC
I-Flash Point: 195.4 ± 20.4 ° C
IMisa Eqondile: 127.038177
I-PSA: 74.50000 Logp: -0.10
Ukubukeka: I-Crystal Emhlophe
Ingcindezi ye-Vapor: 0.0 ± 0.9 Mmhg ngo-25 ° C
I-Index Resuactive: 1.592
Imibandela yokugcina: Ivalwe endaweni epholile neyomile ye-0-6 ºC
Ukuqina: Ngeke kuhlaze lapho kusetshenziswa futhi kugcinwe ngokuya ngemigomo.
| ukucacisa | umuvo | -vamile |
| Ukubonakala | Njengempuphu emhlophe noma ephuzi | |
| -Delile | % | ≥99% |
| Ubumanzi | % | ≤0.3 |
| Sumbomvana | % | ≤0.3 |
Isetshenziswa ikakhulukazi ekuhlanganiseni kweMetronidazole, i-Minotazole nezinye izidakamizwa eziphakathi.
Itholakala ngokuncipha kwe-2-methylimidazole. Beka i-sulfuric acid, 2-methylimidazole ne-sodium sulfate ebhodweni lokuphendula, ivuse futhi ukushisa, engeza i-nitric acid ngo-150-160 ℃, engeza, landela ukuphendula kwe-casket kwehora eli-1. Susa izinga lokushisa libe ngu-140 ℃ ngezansi, ngemuva kokungeza amanzi namanzi e-ammonia ukulungisa i-PH kuya ku-3.5-4, i-crystallization. Qina, geza ongathathi hlangothi, womile, 2-methyl-5-nitroimidazole.
Isikhwama sephepha se-25k kraft noma isikhwama solukiwe (58 × 110) sifakwe esikhwameni sepulasitiki, isikhwama se-250kg sokuthumela ngaphandle (100 × 80); Ngokwezidingo zamakhasimende;
Isitoreji esivaliwe, esigcinwe endaweni yokugcina izinto epholile, emnyama, eyomile, ukugcinwa nokuhamba kufanele kube ukukhanya, ukuvikela ukulimala kanye nokuvimbela ukulimala kanye nomswakama, kuvinjelwe ngokuphelele ngezidakamizwa ezixubile.
Indlela yokukhiqiza: etholwe yi-nitnation of 2-methylimidazole. Beka i-sulfuric acid, 2-methylimidazole ne-sodium sulfate ebhodweni lokuphendula, ivuse futhi ukushisa, engeza i-nitric acid ngo-150-160 ℃, engeza, landela ukuphendula kwe-casket kwehora eli-1. Susa izinga lokushisa libe ngu-140 ℃ ngezansi, ngemuva kokungeza amanzi namanzi e-ammonia ukulungisa i-PH kuya ku-3.5-4, i-crystallization. Qina, geza ongathathi hlangothi, womile, 2-methyl-5-nitroimidazole.
