C17H25N5O7 Guanosine, 2′-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)- (9CI, A CI)
| Izici Zomzimba Eziyinhloko | Inani | Isimo |
| Isisindo samangqamuzana | 411.41 | - |
| I-Melting Point (Eyokuhlola) | 137-139.2 °C | - |
| Ukuminyana (Kubikezelwe) | 1.60±0.1 g/cm3 | Izinga lokushisa: 20 °C; Cindezela: 760 Torr |
| pKa (Kubikezelwe) | 8.68±0.20 | Izinga Le-Acidic Elikhulu: 25 °C |
I-Canonical AMAMOTHEKA O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(CO)C(O)C3OCCOC
I-Isomeric IMILESI O=C1C2=C(N(C=N2)[C@H]3[C@H](OCCOC)[C@H](O)[C@@H](CO)O3)NC(NC (C(C)C)=O)=N1
I-InChI
I-InChI=1S/C17H25N5O7/c1-8(2)14(25)20-17-19-13-10(15(26)21-17)18 -7-22(13)16-12(28-5-4-27-3)11(24)9(6-23)29-16/h7-9,11-12,16,23- 24H,4-6H2,1-3H3,(H2,19,20,21,25,26)/t9-,11-,12-,16-/m1/s1
Ukhiye we-InchI
IZOOGJIUOCHAAY-UBEDBUPSSA-N
1 Elinye Igama lale nto
I-2′-O-(2-Methoxyethyl)-N-(2-methyl-1-oxopropyl) guanosine (ACI)
| Izakhiwo ezitholakalayo |
| Okushisayo |
Okushisayo
| Impahla | Inani | Isimo | Umthombo |
| I-Melting Point | 137-139.2 °C | (1) I-CAS | |
(1) Taj, Shabbir Ali S.; I-Nucleosides, Nucleotides & Nucleic Acids, (2008), 27(9), 1024-1033, CAplus
I-Spectra iyatholakala
1H NMR
13C NMR
IR
| Izakhiwo ezitholakalayo |
| I-Biological |
| Amakhemikhali |
| Ukuminyana |
| I-Lipinski |
| Okuhlobene Nesakhiwo |
I-Biological
| Impahla | Inani | Isimo | Umthombo |
| I-Bioconcentration Factor | 1.0 | i-pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| I-Bioconcentration Factor | 1.0 | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Amakhemikhali
| Impahla | Inani | Isimo | Umthombo |
| Koc | 1.0 | i-pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 1.01 | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 5.81 | pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 11.4 | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 12.6 | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 12.7 | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 12.5 | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 10.6 | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 4.20 | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| Koc | 1.0 | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -2.44 | i-pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -1.60 | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.84 | pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.55 | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.50 | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.50 | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.51 | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.58 | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -0.98 | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| logD | -1.76 | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| logP | -0.497±0.633 | Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Intrinsic Solubility | 0.58 g/L | Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 49g/L | i-pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 7.0 g/L | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 1.2 g/L | pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 0.62 g/L | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 0.58 g/L | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 0.58 g/L | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 0.58 g/L | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 0.70 g/L | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 1.7 g/L | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| I-Mass Solubility | 10 g/L | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| Impahla | Inani | Isimo | Umthombo |
| I-Mass Solubility | 0.58 g/L | Amanzi Angakhiqiziwe pH 5.98; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Intrinsic Solubility | 1.4 x 10-3 mol/L | Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 0.12 mol/L | i-pH 1; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 0.017 mol/L | pH 2; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 3.0 x 10-3 mol/L | pH 3; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 1.5 x 10-3 mol/L | i-pH 4; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 1.4 x 10-3 mol/L | pH 5; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 1.4 x 10-3 mol/L | pH 6; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 1.4 x 10-3 mol/L | pH 7; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 1.7 x 10-3 mol/L | pH 8; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 4.2 x 10-3 mol/L | pH 9; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 0.025 mol/L | pH 10; Izinga lokushisa: 25 °C | (1) ACD |
| I-Molar Solubility | 1.4 x 10-3 mol/L | Amanzi Angakhiqiziwe pH 5.98; Izinga lokushisa: 25 °C | (1) ACD |
| Isisindo samangqamuzana | 411.41 | ||
| pKa | 8.68±0.20 | Izinga Le-Acidic Elikhulu: 25 °C | (1) ACD |
| pKa | 3.05±0.20 | Izinga Lokushisa Eziyisisekelo: 25 °C | (1) ACD |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Ukuminyana
| Impahla | Inani | Isimo | Umthombo |
| Ukuminyana | 1.60±0.1 g/cm3 | Izinga lokushisa: 20 °C; Cindezela: 760 Torr | (1) ACD |
| Ivolumu ye-Molar | 256.2±7.0 cm3/mol | Izinga lokushisa: 20 °C; Cindezela: 760 Torr | (1) ACD |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
I-Lipinski
| Impahla | Inani | Isimo | Umthombo |
| Amabhondi Ashintshashintshayo Ngokukhululekile | 9 | (1) ACD | |
| H Abamukelayo | 12 | (1) ACD | |
| H Abanikeli | 4 | (1) ACD | |
| H Isamba Somnikeli/Umamukeli | 16 | (1) ACD | |
| logP | -0.497±0.633 | Izinga lokushisa: 25 °C | (1) ACD |
| Isisindo samangqamuzana | 411.41 |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Okuhlobene Nesakhiwo
| Impahla | Inani | Isimo | Umthombo |
| Indawo ye-Polar Surface | 157 A2 | (1) ACD | |
(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
I-Spectra iyatholakala
1H NMR
13C NMR
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![C48H54N7O8P Adenosine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – O-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphor amidite] (ACI)](https://cdn.globalso.com/nvchem/C48H54N7O8P-300x300.png)
![C41H51N5O8Si Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)- (9CI, ACI )](https://cdn.globalso.com/nvchem/C41H51N5O8Si-Guanosine-300x300.jpg)
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