isosorbide nitrate
Ulwazi Oluyisisekelo:
Igama lekhemikhali: isosorbide dinitrate; 1,4:3, 6-didehydration D-sorbitan dinitrate
Inombolo ye-CAS: 87-33-2
Ifomula yemolekyuli: C6H8N2O8
Isisindo se-molecule: 236.14
Inombolo ye-EINECS: 201-740-9
Ifomula yesakhiwo:
Izigaba ezihlobene: izinto zokusetshenziswa; Abaphakathi kwezemithi; Izinto zokusetshenziswa kwemithi.
Iphuzu elincibilikayo: 70 °C (lit.)
Indawo yokubilisa: 378.59°C (isilinganiso esinzima)
Ukuminyana: 1.7503 (isilinganiso esinzima)
Inkomba ye-Refractive: 1.5010 (isilinganiso)
Iphoyinti elikhanyayo: 186.6±29.9 ℃
Ukunyibilika: Incibilika ku-chloroform, i-acetone, inyibilika kancane ku-ethanol, inyibilika kancane emanzini.
Izakhiwo: I-crystalline powder emhlophe noma emhlophe, ayinaphunga.
Umfutho womhwamuko: 0.0±0.8 mmHg ku-25℃
| ukucaciswa | iyunithi | ejwayelekile |
| Ukubukeka | I-crystalline powder emhlophe noma emhlophe | |
| Ubumsulwa | % | ≥99% |
| Umswakama | % | ≤0.5 |
I-Isosorbide nitrate iyi-vasodilator isenzo sayo esiyinhloko se-pharmacological siwukuphumuza imisipha ebushelelezi yemithambo. Umphumela ophelele uwukunciphisa ukusetshenziswa komoya-mpilo kwemisipha yenhliziyo, ukwandisa ukunikezwa komoya-mpilo, futhi kudambise i-angina pectoris. Umtholampilo ungasetshenziswa ukwelapha izinhlobo ezahlukene ze-coronary heart disease angina pectoris nokuvimbela ukuhlaselwa. I-drip efakwa emthanjeni ingasetshenziswa ekwelapheni ukumelwa yinhliziyo, izinhlobo ezahlukene zomfutho wegazi ophezulu ezimeni eziphuthumayo kanye nokulawula umfutho wegazi ophakeme wangaphambi kokuhlinzwa.
25g/ isigubhu, isigubhu sekhadibhodi; Isitoreji esivaliwe, izinga lokushisa eliphansi komoya kanye nendawo yokugcina impahla eyomile, ingashi, isitoreji esihlukene ne-oxidizer.
