I-Sulfadiazine

umkhiqizo

I-Sulfadiazine

Ulwazi Oluyisisekelo:

Igama lesiShayina: Sulfadiazine

Isibizo sesiShayina: N-2-pyrimidinyl-4-aminobenzenesulfonamide; i-sulfadiazine-D4; Da'anjing; i-sulfadiazine; 2-p-aminobenzenesulfonamidei-pyrimidine;

Igama lesiNgisi: sulfadiazine

Isibizo sesiNgisi: Sulfadiazine; A-306; I-Benzenesulfonamide, i-4-amino-N-2-pyrimidinyl-; I-Adiazin; rp2616; PYRIMAL; i-sulphadiazine; i-Diazin; I-DIAZYL; DEBENAL; 4-Amino-N-pyrimidin-2-yl-benzenesulfonamide; SD-Na; I-Trisem;

Inombolo ye-CAS: 68-35-9

Inombolo yomthetho: MFCD00006065

Inombolo ye-EINECS: 200-685-8

Inombolo ye-RTECS: WP1925000

Inombolo ye-BRN: 6733588

Inombolo ye-PubChem: 24899802

Ifomula yemolekyuli: C 10 H 10 N 4 O 2 S


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izinkomba

1. I-Sulfadiazine umuthi ongawukhetha wokuqala wokuvimbela nokwelapha i-meningococcal meningitis (i-epidemic meningitis).
2. I-Sulfadiazine ibuye ilungele ukwelapha izifo zokuphefumula, izifo zamathumbu kanye nezifo zezicubu ezithambile zendawo ezibangelwa amagciwane azwelayo.
3. I-Sulfadiazine ingasetshenziswa futhi ukwelapha i-nocardiosis, noma isetshenziswe ngokuhambisana ne-pyrimethamine ukwelapha i-toxoplasmosis.

Izici

Lo mkhiqizo uyikristalu emhlophe noma emhlophe noma impushana; ayinaphunga futhi ayinambitheki; umbala wayo uba mnyama kancane kancane lapho uchayeke ekukhanyeni.
Lo mkhiqizo uncibilika kancane ku-ethanol noma i-acetone, futhi cishe awuncibiliki emanzini; Incibilika kalula kusixazululo sokuhlola i-sodium hydroxide noma isixazululo sokuhlola i-ammonia, futhi inyibilika ku-dilute hydrochloric acid.

sebenzisa

Lo mkhiqizo uyi-sulfonamide esebenza kahle kakhulu ekwelapheni izifo zesistimu . Ine-spectrum ebanzi ye-antibacterial futhi inemiphumela evimbela kumagciwane amaningi e-Gram-positive kanye nama-negative. Ivimbela i-Neisseria meningitidis, i-Streptococcus pneumoniae, i-Neisseria gonorrhoeae, ne-hemolytic Streptococcus. Inomphumela oqinile futhi ingangena oketshezini lwe-cerebrospinal ngokusebenzisa umgoqo wegazi nobuchopho.
Isetshenziswa kakhulu emtholampilo we-meningococcal meningitis futhi iwumuthi okhethwayo ekwelapheni i-meningococcal meningitis. Ingakwazi futhi ukwelapha ezinye izifo ezibangelwa yibhaktheriya ezwelayo eshiwo ngenhla. Ibuye yenziwe ibe usawoti wesodium oncibilikayo emanzini futhi isetshenziswe njengomjovo.


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