I-methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate: izakhiwo kanye nokusebenza

I-Methyl 2,2-FIFLUOOROBEZONO [D] [1,3] dioxole-5-carboxylateiyingxenye yamakhemikhali ngefomula ye-molecular c9h6f2o4 kanye nenombolo ye-CAS 773873-95-3. Yaziwa nangokuthi izimboniso eziningana ezifana, njenge-methyl 2,2-difluoro-1,3-benzodioxole-5-carboxybole, 5,2-carluorobenzodio acid methyl ester, ne-EOS-61003. Kungokwesigaba sezinhlanganisela ze-heterocyclic nge-oxygen hetero-athomu kuphela.

Ukuqhaqhazela ubumsulwa be-98% ubuncane, leli ngxenye yebanga-grade-grade liyisixazululo esiguquguqukayo sezimboni ezinjengezimboni, i-agrochemicals kanye nokucwaninga.

Kulesi sihloko, sizochaza izakhiwo zemikhiqizo enemininingwane nokusebenza kwe-methyl 2,2-difluorobenzo [D] [1,3] diobole-5-carboxylate, ngokusekelwe kwidatha etholakalayo.

Izakhiwo Zomzimba Nezamakhemikhali

I-Methyl 2,2-Difluorobenzo [D] [1,3] Dioxole-5-Carboxylate iyi-colorless engenabala ku-blowel uketshezi noma okuqinile, kuya ngokushisa kanye nobumsulwa. Inesisindo se-molecular sama-216.14 g / mol kanye nobude be-1.5 ± 0.1 g / cm3. Inendawo ebilayo engu-227.4 ± 40.0 ° C ku-760 mmHG nephuzu le-88.9 ± 22.2 ° C. Inengcindezi ephansi ye-vapor ye-0.1 Inenani le-P inani le-3.43, elibonisa ukuthi lincibilikisa kakhulu ku-organic solvents kunasemanzini.

Isakhiwo se-methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate siqukethe i-benzene ring ehlanganiswe nendandatho eyi-1,3-dioole, enama-athomu amabili we-fluorine kanye neqembu le-carboxylate elinamathiselwe kwindandatho ye-benzene. Ukuba khona kwama-athomu ama-fluorine kwandisa ukuqina kanye nokusebenzisa kabusha kwe-compound, kanye ne-lipophility yayo kanye ne-bioavailability. Iqembu le-carboxylate lingasebenza njengeqembu elishiya noma i-nucleophile ekuphendukeni okuhlukahlukene. Indandatho eyi-1,3-dioxole ingasebenza njenge-glycol efakwe imaski noma i-dieveophile ekuphendukeni kwe-cycOadlition.

Ukuphepha nokusingatha

I-Methyl 2,2-Difluorobenzo [D] [1,3] dioxole-5-carboxylate ihlukaniswa njengento enobungozi ngokusho kohlelo lomhlaba jikelele lokuhlukaniswa kwamakhemikhali (amabhele). Inezitatimende zobungozi ezilandelayo nezitatimende zokuphepha:

• I-H315: Ibangela ukucasuka kwesikhumba

• I-H319: Ibangela ukucasuka okukhulu kwamehlo

• I-H335: ingadala ukucasuka okuphefumula

• I-P261: Gwema ukuphefumula uthuli / fuume / igesi / inkungu / amaphunga / isifutho

• I-P305 + P351 + P338: Uma emehlweni: Hlambulula ngokucophelela ngamanzi imizuzu eminingana. Susa ama-lens okuxhumana, uma wethula futhi kulula ukukwenza. Qhubeka u-rinsing

• I-P302 + P352: Uma esikhunjeni: Geza ngensipho eningi namanzi

Izindlela zokuqala zosizo lwe-methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carbox yboxylate kanjena:

• Ukuphefumula: Uma kufakwe ngaphakathi, hambisa isiguli emoyeni omusha. Uma ukuphefumula kunzima, nikeza umoya-mpilo. Uma kungaphefumuli, nikeza ukuphefumula kokufakelwa. Thola Ukunakekelwa Kwezokwelapha

• Ukuxhumana kwesikhumba: Susa izingubo ezingcolisiwe bese ugeza isikhumba kahle ngensipho nangamanzi. Uma uzizwa ungakhululekile, funa ukwelashwa

Ukuthintwa ngamehlo: Amasheya ahlukene futhi ahlanze ngamanzi agijimayo noma usawoti ojwayelekile. Funa ukunakekelwa kwezokwelashwa ngokushesha

• Ukungenisa: Hlanganisa, unganaki ukugabha. Funa ukunakekelwa kwezokwelashwa ngokushesha

Izindlela zokuvikela umlilo ze-methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carbox motos imi ngale ndlela elandelayo:

• Umenzeli ocile: ucime umlilo ngephutha lamanzi, i-powder eyomile, igwebu noma i-carbon dioxide decitive ejele. Gwema ukusebenzisa amanzi aphathelene ngqo nokucisha umlilo, ongadala ukugeleza koketshezi ovuthayo futhi asakaze umlilo

• Izingozi ezikhethekile: Ayikho idatha etholakalayo

• Izindlela zokuvikela umlilo nezindlela zokuvikela: Izisebenzi zomlilo kufanele zigqoke izinto zokuphefumula zomoya, zigqoke izingubo zomlilo ezigcwele, futhi zilwe umlilo phezulu. Uma kungenzeka, hambisa isitsha kusuka emlilweni uye endaweni evulekile. Iziqukathi endaweni yomlilo kumele zikhishwe ngokushesha uma zidilizwa noma zikhanyisa umsindo kusuka kudivayisi yokusiza ukuphepha. Hlukanisa indawo yengozi futhi wenqabe abasebenzi abangafanele ukungena. Aqukethe futhi uphathe amanzi omlilo ukuvikela ukungcoliswa kwemvelo

Ukugcina

I-Methyl 2,2-Difluorobenzo [D] [1,3] dioxole-5-carboxylate ngumphakathi oyisihluthulelo ekuhlolweni kwemithi, ukudalwa kwemikhiqizo yokuvikela izitshalo, nocwaningo lwesayensi. Inesakhiwo esiyingqayizivele enama-athomu amabili we-fluorine neqembu le-carboxylate elinamathele kwindandatho ye-benzodioxole, enikeza ukuqina, ukusebenziseka, ubutha, ubuthakathi, kanye ne-bioavailability ku-compound. Inengcindezi ephansi yamanzi nengcindezi ye-vapor, nephuzu elibilayo elilinganiselayo ne-flash point. Kuhlukaniswa njengento enobungozi futhi kudinga ukuphathwa okufanele nokugcinwa okufanele. Inezinhlelo zokusebenza ezingaba khona ezimbonini ezahlukahlukene, ezinjengemithi, ama-agrochemicals, ucwaningo kanye nabanye.

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