I-Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate: Izakhiwo Nokusebenza

I-Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylateiyinhlanganisela yamakhemikhali enefomula ye-molecular C9H6F2O4 kanye nenombolo ye-CAS 773873-95-3.Kubuye kwaziwe ngamagama afanayo amaningana, njenge-methyl 2,2-difluoro-1,3-benzodioxole-5-carboxylate, 2,2-difluorobenzodioxole-5-carboxylic acid methyl ester, kanye ne-EOS-61003.Kungokwesigaba sama-heterocyclic compounds ane-oxygen hetero-athomu kuphela.

Njengoba iziqhenya ngobumsulwa obungu-98% obuncane, le nhlanganisela yezinga lezemithi iyisixazululo esiguquguqukayo sezimboni ezifana nemithi, amakhemikhali ezolimo, kanye nocwaningo.Le nhlanganisela isetshenziswa njengesihluthulelo esimaphakathi ekuhlanganiseni kwemithi, ekwakhiweni kwemikhiqizo yokuvikela izitshalo, kanye nocwaningo lwesayensi.

Kulesi sihloko, sizochaza izici zomkhiqizo ezinemininingwane nokusebenza kwe-methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate, ngokusekelwe kudatha etholakalayo.

Izakhiwo Zomzimba Nezamakhemikhali

I-Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate iwuketshezi olungenambala ukuya kokuphuzi okuphaphathekile noma oluqinile, kuye ngezinga lokushisa nobumsulwa.Inesisindo sengqamuzana esingu-216.14 g/mol kanye nokuminyana okungu-1.5±0.1 g/cm3.Inephuzu lokubilisa elingu-227.4±40.0 °C ku-760 mmHg kanye nephuzu elikhanyayo elingu-88.9±22.2 °C.Inomfutho ophansi womhwamuko ongu-0.1±0.4 mmHg ku-25°C kanye nokuncibilika okuphansi kwamanzi okungu-0.31 g/L ku-25°C.Inenani elingu-P elingu-3.43, okubonisa ukuthi inyibilika kakhulu kuzincibilikisi zemvelo kunasemanzini.

Isakhiwo se-methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate siqukethe iringi ye-benzene ehlanganiswe nendandatho engu-1,3-dioxole, enama-athomu amabili e-fluorine kanye neqembu le-carboxylate elixhunywe kwiringi ye-benzene. .Ukuba khona kwama-athomu e-fluorine kukhulisa ukuzinza kanye nokusebenza kabusha kwe-compound, kanye ne-lipophilicity yayo kanye ne-bioavailability.Iqembu le-carboxylate lingasebenza njengeqembu elishiya noma i-nucleophile ngokusabela okuhlukahlukene.Indandatho ye-1,3-dioxole ingasebenza njenge-glycol efihliwe noma i-dienophile ekuphenduleni kwe-cycloaddition.

Ukuphepha Nokuphatha

I-Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate ihlukaniswa njengento eyingozi ngokuvumelana ne-Global Harmonized System of Classification and Labeling of Chemicals (GHS).Inalezi zitatimende zezingozi ezilandelayo kanye nezitatimende zokuphepha:

• I-H315: Ibangela ukucasuka kwesikhumba

• I-H319: Ibangela ukucasuka kwamehlo okubi kakhulu

• H335: Ingabangela ukucasuka kokuphefumula

• P261: Gwema ukuphefumula uthuli/umusi/igesi/inkungu/umhwamuko/spray

• P305+P351+P338: UMA EMEHLWENI: Hlanza ngokucophelela ngamanzi imizuzu embalwa.Susa amalensi oxhumana naye, uma ekhona futhi kulula ukuwenza.Qhubeka uhlanza

• P302+P352: UMA ESESIKHUmbeni: Geza ngensipho eningi namanzi

Izinyathelo zosizo lokuqala ze-methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate zimi kanje:

• Ukuhogela: Uma uhogeliwe, yisa isiguli emoyeni omusha.Uma ukuphefumula kunzima, nikeza umoya-mpilo.Uma ungaphefumuli, nikeza ukuphefumula okwenziwa.Thola usizo lwezempilo

• Ukuthinta isikhumba: Khipha izingubo ezingcolile bese ugeza isikhumba kahle ngensipho namanzi.Uma uzizwa ungakhululekile, funa usizo lwezokwelapha

• Ukuthintana kwamehlo: Hlukanisa amajwabu amehlo bese uwageza ngamanzi ahambayo noma ngosawoti ovamile.Funa usizo lwezokwelapha ngokushesha

• Ukugwinya: Gcoba, ungabangeli ukuhlanza.Funa usizo lwezokwelapha ngokushesha

Izinyathelo zokuvikela umlilo ze-methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate zimi kanje:

• Into yokucima umlilo: Cisha umlilo ngenkungu yamanzi, impushana eyomile, igwebu noma into ecisha isikhutha.Gwema ukusebenzisa amanzi agelezayo aqondile ukuze ucime umlilo, okungase kubangele ukuchaphazeka koketshezi oluvuthayo futhi kusabalalise umlilo.

• Izingozi ezikhethekile: Ayikho idatha etholakalayo

• Izinyathelo zokuphepha zomlilo nezindlela zokuzivikela: Izisebenzi zomlilo kufanele zigqoke izinto eziphefumula umoya, zigqoke izingubo ezigcwele umlilo, futhi zilwisane nomoya oshisayo.Uma kungenzeka, susa isitsha emlilweni usiyise endaweni evulekile.Iziqukathi ezisendaweni yomlilo kufanele zikhishwe ngokushesha uma ziguquliwe noma zikhipha umsindo emshinini wokusiza wezokuphepha.Hlukanisa indawo yengozi futhi uvimbele abasebenzi abangabalulekile ukuthi bangene.Gcina futhi uphathe amanzi omlilo ukuze uvimbele ukungcoliswa kwemvelo

Isiphetho

I-Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate iyisihluthulelo esimaphakathi ekuhlanganiseni kwemithi, ukwakhiwa kwemikhiqizo yokuvikela izitshalo, kanye nocwaningo lwesayensi.Inesakhiwo esiyingqayizivele esinama-athomu amabili e-fluorine kanye neqembu le-carboxylate elixhunywe kwindandatho ye-benzodioxole, enikeza ukuzinza, ukusebenza kabusha, i-lipophilicity, kanye ne-bioavailability ku-compound.Inoncibilika kalula emanzini kanye nomfutho womhwamuko, nendawo yokubilisa emaphakathi kanye nephuzu elikhanyayo.Ihlukaniswa njengento eyingozi futhi idinga ukuphathwa nokugcinwa okufanele.Inezinhlelo zokusebenza ezingase zibe khona ezimbonini ezahlukahlukene, njengezemithi, i-agrochemicals, ucwaningo, nezinye.

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